Immunology Interview Question:

Give some general features of antigen-antibody interaction.

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1. The reaction is specific and antigen combines only with its corresponding antibody and vice versa.
2. Entire molecules react but not the fragment.
3. There is no denaturation of antigen or antibody during the reaction.
4. The combination of antigen - antibody is firm but reversible. The firmness of the reaction is influenced by the affinity and avidity of the reaction.
5. Both antigens and antibodies participate in the formation of agglutination and precipitation reactions.
6. Antigens and antibodies can combine in various proportions unlike chemicals with fixed valancy.
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