Bioinformatics Interview Question:

Are all members of transporter families confined to a particular organelle or to the plasma membrane, or are some family members found throughout cellular compartments in eukaryotes?

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Mitochondrial carriers are restricted to certain eukaryotic organelles. Not a single one appears to be a constituent of the plasma membrane, endoplasmic reticulum, Golgi apparatus, or nuclear membrane. Instead, they are found in a subset of organelles, including mitochondria, peroxisomes, amyloplasts, and hydrogenosomes. Are other families similarly restricted? Some of them, such as members of the cystine transporter family, are probably restricted to the intracellular vesicular membranes of eukaryotes, whereas other families can be found in the plasma membrane as well as in various organelles.
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