Immunology Interview Question:

Briefly describe about size of a molecule, which make a substance antigenic.

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Molecule size of an antigen has a direct relation to antigenesity. Very large molecules such as haemocyanin (6.7 million Daltons) and thymoglobulin (669 kd) are highly antigenic where as low molecular weight compounds whose molecular weight is less than 10,000 Daltons are poor antigenic. Ex: Insulin and histones
Submitted by: Administrator