Top Pharma Exam Interview Questions & Answers:

1. What drug(s) inhibit the second stage of the cell wall synthesis? (Precursor transported from inside cell membrane to outside)

Vancomycin and Bacitracin

2. What drug(s) inhibit the third stage of the cell wall synthesis? (Cross linking of the cell wall)?

Penicillin and Cephalosporin

3. What does Cell Death require?

Action of Autolysin

4. What are three mechanisms of resistance to Penicillin?

Lack of accessibility to target (Gram Negative)

Production of Penicillinases (Beta-Lactamase)

Alterations in Penicillin Binding Proteins

5. About what percent of penicillin is protein bound?

33-50%

6. What is the standard reference of Penicillin?

Penicillin G

7. Is oral use of Penicillin G indicated?

Not, it is inactivated at low pH

8. Which type of Pen G is used for syphyllis and rheumatic fever prophylaxis?

Benzathine Pen G

9. Which type of Pen G is used for the treatment of ghonorrea?

Procaine Pen G

10. Which type of penicillin is acid stable?

Penicillin V