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Microbiology Interview Question:
This year a report from India indicates that a single dose of Amphotericin B can result in the cure of Leishmania donovani rather than prolonged treatment by fairly toxic medication. If confirmed this will be a major advance in the treatment of Kala-azar. Which of the following statements is false regarding systemic Leishmaniasis?
Submitted by: Administrator* A. It is spread by the bite of the sand fly
* B. Macrophages ingest the organism and move about the body facilitating its spread
* C. Diagnosis can often be made by identifying amastigotes in cells aspirated from the spleen or bone marrow
* D. Untreated patients frequently recover themselves
* E. Kala-azar should be considered as one of the possibilities in someone who has lived in an endemic area and has an enlarged spleen
Correct Answer: D
Submitted by: Administrator
* B. Macrophages ingest the organism and move about the body facilitating its spread
* C. Diagnosis can often be made by identifying amastigotes in cells aspirated from the spleen or bone marrow
* D. Untreated patients frequently recover themselves
* E. Kala-azar should be considered as one of the possibilities in someone who has lived in an endemic area and has an enlarged spleen
Correct Answer: D
Submitted by: Administrator
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