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Cell Biology Interview Question:
What are the primary and the secondary constrictions of a chromosome? What is the other name given to the secondary constriction?
Submitted by: AdministratorPrimary constriction is the narrower region of a condensed chromosome where the centromere, the structure that unites identical chromatids, is located. Secondary constriction is a region similar to the primary constriction, narrower than the normal thickness of the chromosome too, and in general it is related to genes that coordinate the formation of the nucleolus and control the ribosomic RNA (rRNA) synthesis. For this reason the secondary contrictions (that can be one or more in chromosome) is called nucleolus organizer region (NOR).
Submitted by: Administrator
Submitted by: Administrator
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