Pathology Interview Questions and Answers

Pathology Questions and Answers:

1 :: Artificial intelligence and data-mining systems often use "training data sets" and "test data sets." Define these terms and describe briefly how these data sets are used.

Training data sets are given to systems initially to teach them to make correct responses. Test data sets are equivalent to the training sets but contain separate data and are used to verify the performance of the systems.
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2 :: Rule-based systems underlie most clinical event monitors (programs that detect important clinical events and notify appropriate medical personnel). Often these systems work in conjunction with data from the clinical pathology LIS. What aspects of clinical pathology make a rule-based system a reasonable approach?

Clinical laboratory databases consist of many discrete test results that have known reference ranges and critical values. Well-established patterns of these results exist that is known as related to important clinical conditions. Writing rules that detect and alert to these patterns is straightforward.
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4 :: What is the Arden syntax?

The Arden syntax is a standard language and format for representing the medical knowledge and algorithms required for making medical decisions. It is used in medical decision support systems.
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5 :: How are neural networks different than Bayesian belief networks along the following dimensions:
(1) inspect ability of knowledge,
(2) need for probabilities acquired from "domain" experts,
(3) need for data to train the system, and
(4) ability of the system to make classifications based on input data. (Note: You may find it helpful to make a 2 × 4 table and include a short phrase or two in each cell.)

Bayesian belief networks are inspectable, known probabilities are required, training data are not needed, and they can classify into multiple categories.

Neural networks are not inspectable, they do not need domain expertise or known probabilities, training data are required, and they are best for a binary classification ("yes" or "no").
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