Outcomes research is often limited in the conclusions that can be drawn because of limitations in the data sources used for the studies. What are the most common data sources and what are their main limitations?
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The most common data sources include large local or regional administrative databases from hospitals, insurers, or government agencies. These databases contain very limited clinical information (usually ICD-9 codes), and thus it is difficult to meaningfully stratify patients by the severity of their illness, particular symptoms or test result characteristics, or the details of their therapy.
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