* A. Uncoating
* B. Virion Assembly
* C. Release by budding
* D. Adsorption
* E. Production of mRNA
Correct Answer: D
2. A cytolytic virus would be expected to cause cytopathic effect in cell culture?
* A. True
* B. False
Correct Answer: A
3. All of the following are true statements regarding viruses EXCEPT?
* A. They contain both RNA and DNA
* B. The nucleic acid may be single or double stranded
* C. They are obligate intracellular parasites
* D. They reproduce using host cell energy
* E. The infectious particle is called a virion
Correct Answer: A
* A. True
* B. False
Correct Answer: B
5. All of the following are syndromes associated with enteroviruses EXCEPT?
* A. Conjuctivitis
* B. Coronary artery disease
* C. Myocarditis
* D. Pericarditis
* E. Pleuritis
Correct Answer: B
6. The following statements are clearly true about enteroviruses EXCEPT?
* A. There are many serotypes
* B. They can cause a variety of diseases which imitate bacterial infection
* C. They are an important cause of meningitis
* D. They are an important cause of diarrhea
Correct Answer: D
7. Enteroviruses are most closely related to which of the following viruses?
* A. Herpes simplex
* B. Hepatitis C
* C. Hepatitis A
* D. Rotavirus
* E. Rubella
Correct Answer: C
8. Foscarnet interacts with which of the following viral enzymes?
* A. Pyrophosphate-binding site of the polymerase
* B. Protease
* C. Nucleoside reductase
* D. Reverse transcriptase
Correct Answer: A
* A. Cleaves polyprotein precursor leading to functional assembly of viral core
* B. Cleaves sialic acid residue from glycoprotein permitting attachment and entry into cell
* C. Transcribes RNA into DNA
* D. Activates 2', 5' oligoadenylate synthetase
Correct Answer: C
* A. Few drug targets, toxicity problematic
* B. Sensitivity tests of limited value
* C. Toxicity a minor problem, multiple enzymatic targets
* D. Many more drug options are available to treat viral infections
Correct Answer: A