How is the calculation derived for a drug to be bioequivalent with other? On which base the limit is fixed as 80-120% for a drug to be bioequivalent. What is meant by 90% confidential interval?
Submitted by: AdministratorTo be "bioequivalent" two preparations or drugs need to give the same biological effect.
The usual "experimental error" put on this is 20% - thus, 80-120% is considered "bioequivalent.”
90 percentage confidence interval means that statistically it is 90% certain that the results are equivalent.
Submitted by: Administrator
The usual "experimental error" put on this is 20% - thus, 80-120% is considered "bioequivalent.”
90 percentage confidence interval means that statistically it is 90% certain that the results are equivalent.
Submitted by: Administrator
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