What are six mechanisms of resistance from chemotherapeutic agents?
Submitted by: Administrator1) Absence of Target (Ergosterol's absent)
2) Alterations in Target (Pen. Binding Protein Alterations)
3) Low concentration at target (Interference with membrane passage)
4) Lack of metabolic activation (Antifungal Flucytosine -> Fluorouracil)
5) Inactivation (Penicillinases)
6) Escape from Effect (Alternate Metabolic Pathways)
Submitted by: Administrator
2) Alterations in Target (Pen. Binding Protein Alterations)
3) Low concentration at target (Interference with membrane passage)
4) Lack of metabolic activation (Antifungal Flucytosine -> Fluorouracil)
5) Inactivation (Penicillinases)
6) Escape from Effect (Alternate Metabolic Pathways)
Submitted by: Administrator
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